By Buddhi Prakash Jain, Shyamal K. Goswami, Tapan Sharma
Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.
Product Details
- Publisher : Academic Press; 1st edition (August 30, 2022)
- Language : English
- Digital eBook : 394 pages
- ISBN-10 : 0323913059
- ISBN-13 : 978-0323913058
- ISBN-13 : 9780323913058
- eText ISBN: 9780323914246
