This guidebook has been edited and rewritten by the present team of ACVIP, maintaining the basic structure of the earlier versions which have been prepared by various stalwarts of vaccinology from all over India. These guidelines have been prepared based on information from medical literature, local epidemiological data and are essentially aimed at uniform and appropriate vaccination practice amongst members of The Indian Academy of Pediatrics (IAP). The schedules recommended for various individual vaccines in this guidebook may differ from those adopted by the government agencies based on scientific data as well as practical considerations and ground realities related to the availability of some of the vaccines.