25 years ago, the faculty from the Departments of Radiodiagnosis of the three premier institutes of the country, All India Institute of Medical Sciences (AIIMS), New Delhi, India; Maulana Azad Medical College (MAMC), New Delhi; and Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, joined hands in a unique endeavor, that led to the first AIIMS-MAMC-PGI Teaching Course Series in the year 1996. The first course series was completed in the year 2000. The popularity of the course led to two more imaging course series, which ended in the years 2005 and 2013, respectively. The overwhelming response to the AIIMS-MAMC-PGI imaging course among students and practicing radiologists continues, leading to its present avatar as the 4th course, which will culminate in its silver jubilee year. Every lecture series in the course, each of which is dedicated to a particular subspecialty of imaging and intervention, is held at one of the three premier institutes and is simultaneously followed by the publication of the book written by the eminent faculty of these institutes.The rapid advances in imaging make it a challenge for the students and practitioners to keep abreast and up-to-date with the latest developments. To incorporate such changes, the current edition of the book dedicated to Musculoskeletal and Breast Imaging has evolved into a textbook with 29 chapters. The experts in the three institutes have thoroughly revised the existing chapters, incorporated recent advances, guidelines and recommendations and new technical advances in imaging and interventions. A simplified approach to understanding relevant anatomy and for optimizing imaging techniques has been incorporated at the beginning of chapters. We hope that this edition will benefit the postgraduate students, residents, radiologists and our clinical colleagues in their daily practice.