Clinical Therapeutics PDF

The International Peer-Reviewed Journal of Drug Therapy

Clinical Therapeutics provides peer-reviewed, rapid publication of recent developments in drug and other therapies as well as in diagnostics, pharmacoeconomics, health policy, treatment outcomes, and innovations in drug and biologics research. In addition Clinical Therapeutics features updates on specific topics collated by expert Topic Editors. Clinical Therapeutics is read by a large international audience of scientists and clinicians in a variety of research, academic, and clinical practice settings. Articles are indexed by all major biomedical abstracting databases.

Published articles range from pivotal studies exploring new chemical entities in large, multicenter trials to those exploring repurposing of marketed agents. Additionally, pilot studies; reports that assess drug safety and tolera-bility in all phases of development; new routes of administration and new formulations; pharmacokinetic, bio-availability, and biosimilarity; and changes in practice guidelines and standards, are all of interest for publication. Clinical Therapeutics also understands the importance of strengthening the body of evidence surrounding particular agents through the publication of replication studies, negative trials, and failed trials.

Beyond the clinic, we seek reports that examine the real-world implications of therapeutics such as comparative effectiveness and pharmacoeconomics studies as well as work that has implications for health policy. Commentaries, which include perspectives and contemporary issues, are sought to offer a balance of viewpoints and scholarly opinion on a broad array of drug-related topics. Case reports, which remain a vital part of our mission, offer clinically valuable lessons. All manuscripts are peer reviewed by independent clinicians or scientists for clinical relevance, technical accuracy, methodological rigor, clarity, and objectivity using a blind review process.

In addition to feature articles published monthly, each issue of Clinical Therapeutics features a specific theme section dedicated to an annual update of a specific topic area. A special guest editor will comprise each update with reviews, commentaries, and original research highlighting what’s new or controversial in the topical specialty. Authors are invited to submit manuscripts for consideration in the topic updates, identifying submissions as such in their cover letters.

Volume 44, Issue 1: Pages 1-154 (January 2022)
Volume 44, Issue 2: Pages 155-348 (February 2022)
Volume 44, Issue 3: Pages 349-472 (March 2022)
Volume 44, Issue 4: Pages 473-638 (April 2022)
Volume 44, Issue 5: Pages 639-824 (May 2022)
Volume 44, Issue 6: Pages 825-926 (June 2022)
Volume 44, Issue 7: Pages 927-1034 (July 2022)
Volume 44, Issue 8: Pages 1035-1172 (August 2022)
Volume 44, Issue 9: Pages 1173-1268 (September 2022)
Volume 44, Issue 10: Pages 1269-1426 (October 2022)
Volume 44, Issue 11: Pages 1427-1548 (November 2022)
Volume 44, Issue 12: Pages 1549-1632 (December 2022)
Volume 45, Issue 1: Pages 1-88 (January 2023)
Volume 45, Issue 2: Pages 89-194 (February 2023)
Volume 45, Issue 3: Pages 195-302 (March 2023)
Volume 45, Issue 4: Pages 303-386 (April 2023)
Volume 45, Issue 5: Pages 387-482 (May 2023)
Volume 45, Issue 6: Pages 483-616 (June 2023)
Volume 45, Issue 7: Pages 617-684 (July 2023)
Volume 45, Issue 8: Pages 685-806 (August 2023)
Volume 45, Issue 9: Pages 807-924 (September 2023)
Volume 45, Issue 10: Pages 925-1014 (October 2023)
Volume 45, Issue 11: Pages 1015-1160 (November 2023)
Volume 45, Issue 12: Pages 1161-1298 (December 2023)
Volume 46, Issue 1: Pages 1-84 (January 2024)
Volume 46, Issue 2: Pages 85-184 (February 2024)
Volume 46, Issue 3: Pages 185-304 (March 2024)
Volume 46, Issue 4: Pages 305-380 (April 2024)
Volume 46, Issue 5: Pages 381-440 (May 2024)
Volume 46, Issue 6: Pages 441-516 (June 2024)
Volume 46, Issue 7: Pages 517-602 (July 2024)
Volume 46, Issue 8: Pages 595-660 (August 2024)
Volume 46, Issue 9: Pages 661-726 (September 2024)